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Product Name
GAPDHS antibody
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Description
GAPDHS Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue. Observed molecular weight by Western-blot: 69kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
GAPD2 antibody; GAPDH 2 antibody; GAPDH2 antibody; GAPDHS antibody; GAPDS antibody; HSD 35 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GAPDHS recombinant protein (Accession Number: NM_014364). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:110865(GAPDHS antibody) at dilution of 1:800
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Background
GAPDHS(Glyceraldehyde-3-phosphate dehydrogenase, testis-specific) is also named as GAPD2, GAPDH2, GAPDS and belongs to the glyceraldehyde-3-phosphate dehydrogenase family. It may play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. GAPDHS is a promising contraceptive target because it is specific to male germ cells, essential for sperm motility and male fertility, and well suited to pharmacological inhibition(PMID:20828617).
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References
- Mukai C, Gao L, Bergkvist M, Nelson JL, Hinchman MM, Travis AJ. Biomimicry enhances sequential reactions of tethered glycolytic enzymes, TPI and GAPDHS. PloS one. 8(4):e61434. 2013.
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