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Product Name
GALT antibody
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Description
GALT Rabbit Polyclonal antibody. Positive IHC detected in human liver tissue. Positive WB detected in human liver tissue. Observed molecular weight by Western-blot: 45-48kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
Gal 1 P uridylyltransferase antibody; GALT antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GALT recombinant protein (Accession Number: NM_000155). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:110853(GALT antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human liver using Catalog No:110853(GALT antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human liver using Catalog No:110853(GALT antibody) at dilution of 1:100 (under 40x lens)
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Background
GALT (galactose-1-phosphate uridylyltransferase) catalyses the second step in the Leloir pathway for the conversion of galactose-l-phosphate (Gal-I-P) into uridine diphosphogalactose (UDP-gal). Defects in GALT cause galactosemia.
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References
- Wen Y, Li J, Tan Y. Angelica Sinensis polysaccharides stimulated UDP-sugar synthase genes through promoting gene expression of IGF-1 and IGF1R in chondrocytes: promoting anti-osteoarthritic activity. PloS one. 9(9):e107024. 2014.
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