GALNS antibody

GALNS antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

GALNS Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue. Positive WB detected in human liver tissue. Observed molecular weight by Western-blot: 50-55kd

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

Chondroitinase antibody; Chondroitinsulfatase antibody; FLJ17434 antibody; FLJ42844 antibody; FLJ98217 antibody; Galactose 6 sulfate sulfatase antibody; GALNAC6S antibody; GalNAc6S sulfatase antibody; GALNS antibody; GAS antibody; MPS4A antibody

Rabbit IgG

This antibody was obtained by immunization of GALNS recombinant protein (Accession Number: NM_000512). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

GALNS(N-acetylgalactosamine-6-sulfatase) is also named as chondroitinase and belongs to the sulfatase family. It is one of sulfatases required to degrade glycosaminoglycans (GAGs), keratan sulfate (KS) and chondroitin-6-sulfate (C6S) and the enzyme is a dimer derived from two 60 kDa polypeptides, each of which is processed to 40 kDa and 15 kDa polypeptide subunits linked by disulfide bonds(PMID:15241807). The deduced 522-residue protein is composed of a 26-amino acid N-terminal signal peptide and a mature polypeptide of 496 amino acid residues, including 2 potential asparagine-linked glycosylation sites(PMID:1755850). Defects in GALNS are the cause of mucopolysaccharidosis type 4A (MPS4A), also known as Morquio A syndrome.