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Product Name
Human Galectin-1 recombinant protein
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Description
May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
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Protein name
Galectin-1
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Protein short names
LECT14; LGALS1; L-14.5; GALBP; GAL1; DKFZP686E23103; AA410090; GAL-1; L14; GALECTIN-1; GBP
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Uniprot ID
P09382
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Gene Name
LGALS1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human Galectin 1 (NP_002296.1) (Met 1-Asp135) was expressed.
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Protein Species
Human
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Molecular weight
The recombinant human Galectin 1 comprises 134 amino acids without the initiator methonine, and predicts a molecular mass of 15 kDa as estimated in SDS-PAGE under reducing conditions.
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Purity
> 98 % as determined by SDS-PAGE
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Activity
Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is typically 0.5-3 μg/ml.
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Validations
Human Galectin-1 / LGALS1 Protein SDS-PAGE
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