GALC antibody

GALC antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

GALC Rabbit Polyclonal antibody. Positive WB detected in A375 cells, HeLa cells, human placenta tissue, mouse brain tissue. Observed molecular weight by Western-blot: 50 kDa

ELISA, WB

Human,Mouse,Rat; other species not tested.

GalactOCerebrosidase antibody; galactosylceramidase antibody; GALC antibody; GALCERase antibody

Rabbit IgG

This antibody was obtained by immunization of GALC recombinant protein (Accession Number: BC036518). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Galactosylceramidase (Galc) is a lysosomal enzyme involved in the catabolism of galactosylceramide, a major lipid in myelin, kidney, and epithelial cells of the small intestine and colon. The normal GALC mRNA encodes the 80 kDa precursor, which is processed into 50 and 30 kDa subunits. Mutation of GALC gene will lead to Krabbe disease (globoid cell leukodystrophy), an autosomal recessive neurodegenerative disorder that affects both the central and peripheral nervous system due to an enzymatic defect of galactocerebrosidase.