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Product Name
GAK antibody
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Description
GAK Rabbit Polyclonal antibody. Positive WB detected in human brain tissue. Observed molecular weight by Western-blot: 150 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
cyclin G assOCiated kinase antibody; FLJ16629 antibody; FLJ40395 antibody; GAK antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GAK recombinant protein (Accession Number: BC008668). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110827(GAK antibody) at dilution of 1:500
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Background
GAK(cyclin-G-associated kinase) belongs to the protein kinase superfamily. GAK plays a more positive role as a modulator of signal transduction, by relaying the phosphorylation signal from an unidentified tyrosine kinase to unidentified GAK phosphorylation targets(PMID:9013862). It may be acting as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by hsc70 in non-neuronal cells.
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