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Product Name
GAD1 antibody
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Description
GAD1 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, mouse brain tissue. Positive IP detected in HEK-293 cells. Observed molecular weight by Western-blot: 67 kDa, 25 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FLJ45882 antibody; GAD antibody; GAD 67 antibody; GAD1 antibody; GAD67 antibody; Glutamate decarboxylase 1 antibody; SCP antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of GAD1 recombinant protein (Accession Number: XM_017003758). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
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Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:110816(GAD1 Antibody) at dilution of 1:600
IP Result of anti-GAD1 (IP:Catalog No:110816, 4ug; Detection:Catalog No:110816 1:500) with HEK-293 cells lysate 3680ug.
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Background
The GAD1(glutamate decarboxylase 1) gene encodes 67 kDa glutamic acid decarboxylase isoform (GAD67), the rate-limiting enzyme responsible for γ-aminobutyric acid (GABA) biosynthesis from glutamatic acid and the major GAD isoform in the human brain for early brain development(PMID:21302352). It is also potentially involved in variety of skin activities. It belongs to the group II decarboxylase family.
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