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Product Name
G0S2 antibody
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Description
G0S2 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells. Positive IF detected in mouse (embryonic day 18) skin tissue.
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Tested applications
ELISA, IF, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
G0/G1switch 2 antibody; G0S2 antibody; RP1 28O10.2 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of G0S2 recombinant protein (Accession Number: NM_015714). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IF: 1:25 - 1:100
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Validations
IF result of G0S2 antibody (Catalog No:110762,1:100, Green) with skin samples (mouse) at embryonic day 18 by Dr. Colin Jahoda.
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:110762(G0S2 Antibody) at dilution of 1:1000
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Background
G0S2 is G0/G1 switch protein 2. It is an all trans- retinoic acid (RA) target gene. G0S2 promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers.
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References
- Louche K, Badin PM, Montastier E. Endurance exercise training up-regulates lipolytic proteins and reduces triglyceride content in skeletal muscle of obese subjects. The Journal of clinical endocrinology and metabolism. 98(12):4863-71. 2013.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"