FYB Polyclonal Antibody

Cat.#: 162965

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Product Information

  • Product Name
    FYB Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to FYB
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    FYB antibody; ADAP antibody; PRO0823 antibody; SLAP-130 antibody; SLAP130 antibody; THC3 antibody; FYN-binding protein antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 678-829 of human FYB (NP_001456.3).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - FYB Polyclonal Antibody

    Western blot - FYB Polyclonal Antibody

    Western blot analysis of extracts of Jurkat cells, using FYB antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 60s.

  • Background
    Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"