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Product Name
FUCA1 antibody
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Description
FUCA1 Rabbit Polyclonal antibody. Positive IHC detected in human liver tissue, human heart tissue, human kidney tissue, human liver cancer tissue, human placenta tissue, human testis tissue.
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Tested applications
ELISA, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Alpha L fucosidase 1 antibody; Alpha L fucosidase I antibody; FUCA antibody; FUCA1 antibody; fucosidase antibody; alpha L 1 antibody; tissue antibody; Tissue alpha L fucosidase antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of FUCA1 recombinant protein (Accession Number: BC017338). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human liver using Catalog No:110790(FUCA1 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human liver using Catalog No:110790(FUCA1 antibody) at dilution of 1:50 (under 40x lens)
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Background
FUCA1(a-l-Fucosidase) is a lysosomal glycosidase which is ubiquitous in eukaryotic cells. This enzyme is usually found as a soluble component of the lysosome and functions as an acid hydrolase in the degradation of numerous and diverse fucoglycoconjugates.The mammalian a-l-fucosidases are relatively large, multisubunit glycoproteins which exist in multiple molecular isoforms.This enzyme may have a role in sperm-egg interactions in the reproductive tract of the female rat. There is a precursor 54 kDa form of rat sperm fucosidase which is processed to a mature 52 kDa form of the enzyme(PMID:8836125). This protein from rat epididymis is a tetramer of 210-220 kDa, made up by two pairs of subunits of 47 and 60 kDa, and the one from human seminal plasma exists in different oligomeric forms, that is, as a dimer, as a tetramer, and as a hexamer made up of a single subunit of 56-57 kDa(PMID:16736526).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"