FMO5 antibody

FMO5 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

FMO5 Rabbit Polyclonal antibody. Positive WB detected in human liver tissue, mouse lung tissue. Positive IP detected in mouse lung tissue. Observed molecular weight by Western-blot: 60 kDa

ELISA, WB, IP

Human,Mouse,Rat; other species not tested.

Dimethylaniline oxidase 5 antibody; FMO 5 antibody; FMO5 antibody

Rabbit IgG

This antibody was obtained by immunization of FMO5 recombinant protein (Accession Number: NM_001144830). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Microsomal flavin-containing monooxygenases (FMOs) [dimethylaniline monooxygenase (N-oxide forming) catalyze the FAD-, NADPH- and O2-dependent oxidation of a large number of structurally diverse compounds, including drugs, pesticides, and industrial chemicals containing a soft nucleophile(PMID:12488558 ). FMO5, which belongs to the FMO family, is a lesser component of human liver microsomes and is present at about one-third the level of FMO3. FMO5 protein is also present at very low levels in kidney, however, FMO5 exhibits a severely restricted substrate specificity for most drugs and other xenobiotics examined to date(PMID:10950857). It has 2 isoforms produced by alternative splicing.

• Gonzalez Malagon SG, Melidoni AN, Hernandez D. The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical pharmacology. 96(3):267-77. 2015.