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Product Name
FKBP1B Polyclonal Antibody
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Description
Polyclonal antibody to FKBP1B
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Tested applications
WB, IHC, IF
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Species reactivity
Human, Mouse, Rat
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Alternative names
FKBP1B antibody; FKBP12.6 antibody; FKBP1L antibody; OTK4 antibody; PKBP1L antibody; PPIase antibody; FK506 binding protein 1B antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide corresponding to a sequence within amino acids 1-80 of human FKBP1B (NP_473374.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100 -
Validations
Western blot - FKBP1B Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using FKBP1B antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 10s.
Immunohistochemistry - FKBP1B Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat heart using FKBP1B antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - FKBP1B Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse spinal cord using FKBP1B antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - FKBP1B Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse heart using FKBP1B antibody at dilution of 1:100 (40x lens).
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Background
Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"