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FKBP1A antibody

Cat.#: 110671

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Product Information

  • Product Name
    FKBP1A antibody
  • Documents
  • Description
    FKBP1A Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, human heart tissue. Positive IHC detected in human ovary tumor tissue. Observed molecular weight by Western-blot: 12-16 kDa
  • Tested applications
    ELISA, IHC, WB
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    12 kDa FK506 binding protein antibody; 12 kDa FKBP antibody; FK506 binding protein 1A antibody; FKBP 12 antibody; FKBP 1A antibody; FKBP1 antibody; FKBP12 antibody; FKBP12C antibody; FKBP1A antibody; Immunophilin FKBP12 antibody; PKC12 antibody; PKCI2 antibody; PPIASE antibody; PPIase FKBP1A antibody; Rotamase antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of FKBP1A recombinant protein (Accession Number: NM_054014). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:110671(FKBP1A antibody) at dilution of 1:100 (under 25x lens)

    Immunohistochemical of paraffin-embedded human ovary tumor using Catalog No:110671(FKBP1A antibody) at dilution of 1:100 (under 25x lens)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110671(FKBP1A Antibody) at dilution of 1:1000

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110671(FKBP1A Antibody) at dilution of 1:1000

  • Background
    FKBP1A(FK506-binding protein 1A) is also named as FKBP1, FKBP12 and belongs to the FKBP-type PPIase family.It keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
  • References
    • Qiu Y, Zhao W, Wang Y. FK506-binding protein 12 modulates μ-opioid receptor phosphorylation and protein kinase C(ε)-dependent signaling by its direct interaction with the receptor. Molecular pharmacology. 85(1):37-49. 2014.
    • Tan SM, Kirchner R, Jin J. Sequencing of captive target transcripts identifies the network of regulated genes and functions of primate-specific miR-522. Cell reports. 8(4):1225-39. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"