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Product Name
Human FGF19 / FGF-19 recombinant protein
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Description
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
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Protein name
Fibroblast growth factor 19
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Protein short names
FGF-19; UNQ334/PRO533
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Uniprot ID
O95750
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Gene Name
FGF19; UNQ334/PRO533
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human FGF19 (O95750) (Phe27-Lys216) was expressed, with a N-terminal Met.
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Protein Species
Human
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Molecular weight
The recombinant human FGF19 consists of 191 amino acids and predicts a molecular mass of 21.4 KDa. It migrates as an approximately 23 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 97 % as determined by SDS-PAGE
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Validations
Human FGF19 Protein SDS-PAGE
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