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Product Name
FGFBP2 antibody
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Description
FGFBP2 Rabbit Polyclonal antibody. Positive IF detected in BxPC-3 cells. Positive WB detected in SH-SY5Y cells, BxPC-3 cells. Observed molecular weight by Western-blot: 37kd
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Tested applications
ELISA, WB, IF
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Species reactivity
Human; other species not tested.
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Alternative names
FGF binding protein 2 antibody; FGF BP2 antibody; FGFBP 2 antibody; FGFBP2 antibody; HBp17 related protein antibody; HBp17 RP antibody; HBP17RP antibody; KSP37 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of FGFBP2 recombinant protein (Accession Number: NM_031950). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
IF: 1:10-1:100
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Validations
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with Catalog No:110638(FGFBP2 antibody) at dilution of 1:400
Immunofluorescent analysis of BxPC-3 cells using Catalog No:110638(FGFBP2 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Background
Fibroblast growth factor-binding protein 2 (FGFBP2), also known as 37 kDa killer-specific secretory protein (KSP37), is a member of the fibroblast growth factor binding protein family. FGFBP2 was identified as a Th1/Tc1 specific secretory protein is expressed preferentially in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells and might be involved in essential processes of CTL-mediated immunity. An increase expression of FGFBP2 may be associated with atopic asthma and mild extrinsic asthma. Recently, an observation revealed that FGFBP2 correlate strongly with histology, stage and outcome in ovarian, and it might be a potential prognostic biomarker. The observed MW of FGFBP2 (37 kDa) varies from the predicated MW of 28 kDa, which may be due to the specific space conformation caused by internal disulfide bonds.
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