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Product Name
FGF12 antibody
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Description
FGF12 Mouse Monoclonal antibody. Positive WB detected in Human brain, human brain tissue. Observed molecular weight by Western-blot: 20 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
FGF 12 antibody; FGF12 antibody; FGF12B antibody; FHF 1 antibody; FHF1 antibody; fibroblast growth factor 12 antibody; MyOCyte activating factor antibody
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Isotype
Mouse IgG2b
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Preparation
This antibody was obtained by immunization of FGF12 recombinant protein (Accession Number: NM_004113). Purification method: Caprylic Acid/Ammonium Sulfate Precipitation.
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Clonality
Monoclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:107207(FGF12 antibody) at dilution of 1:1000
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Background
FGF12 is a member of the fibroblast growth factor (FGF) family. FGF family members play important roles in embryogenesis, angiogenesis, and wound repair. FGF12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. FGF12 plays an intracellular role in the inhibition of radiation-induced apoptosis. FGF12 is expressed abundantly in developing and adult nervous systems; therefore, FGF12 was thought to be related to nervous system development and function.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"