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Product Name
FDXR Polyclonal Antibody
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Description
Polyclonal antibody to FDXR
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Tested applications
WB, IHC
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Species reactivity
Human, Mouse, Rat
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Alternative names
FDXR antibody; ADXR antibody; ferredoxin reductase antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 252-491 of human FDXR (NP_077728.3).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:100 - 1:200 -
Validations
Western blot - FDXR Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using FDXR antibody at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit ._Exposure time: 30s.
Immunohistochemistry - FDXR Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human liver cancer using FDXR antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - FDXR Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human esophagus using FDXR antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - FDXR Polyclonal Antibody
Immunohistochemistry of paraffin-embedded human stomach using FDXR antibody at dilution of 1:100 (40x lens).
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Background
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"