FBXW4 antibody

FBXW4 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

FBXW4 Rabbit Polyclonal antibody. Positive WB detected in mouse lung tissue, mouse liver tissue. Observed molecular weight by Western-blot: 50 kDa

ELISA, WB

Human,Mouse,Rat; other species not tested.

DAC antibody; Dactylin antibody; FBW4 antibody; FBWD4 antibody; FBXW4 antibody; SHFM3 antibody; SHSF3 antibody

Rabbit IgG

This antibody was obtained by immunization of FBXW4 recombinant protein (Accession Number: BC007380). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins, and they are a family of eukaryotic proteins characterized by an approximately 40 amino acid motif. SCF complex, a class of ubiquitin ligases, consists of invariable components, Skp1 and Cullin, and variable components of F-box proteins, which have a primary role in determining substrate specificity. FBXW4, also known as SHFM3, encodes F-box and WD-40 domain-containing protein 4. Defects in SHFM3 are a cause of split-hand/foot malformation type 3 (SHFM3), an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.