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Product Name
FBXW2 antibody
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Description
FBXW2 Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue. Positive IHC detected in human colon cancer tissue. Observed molecular weight by Western-blot: 52 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FBW2 antibody; FBXW2 antibody; Fwd2 antibody; Md6 antibody; Protein MD6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of FBXW2 recombinant protein (Accession Number: NM_012164). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:110563(FBXW2 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:110563(FBXW2 antibody) at dilution of 1:50 (under 10x lens)
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Background
The human FBW2 polypeptide contains an N-terminal F-box motif and a C-terminal domain of five WD repeats. A WD repeat is a motif typically consisting of 44-60 amino acids with a signature tryptophan and aspartic acid dipeptide at its C-terminus. The WD repeats in FBW2 recognize GCM1 in a way that is facilitated by GSK3β.
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