-
Product Name
FBXO9 antibody
- Documents
-
Description
FBXO9 Rabbit Polyclonal antibody. Positive IHC detected in human prostate cancer tissue. Positive WB detected in human liver tissue. Observed molecular weight by Western-blot: 52 kDa
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
dJ341E18.2 antibody; DKFZp434C0118 antibody; F box only protein 9 antibody; F box protein 9 antibody; FBX9 antibody; FBXO9 antibody; KIAA0936 antibody; NY REN 57 antibody; VCIA1 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of FBXO9 recombinant protein (Accession Number: NM_033481). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
-
Validations
human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:110560(FBXO9 antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:110560(FBXO9 antibody) at dilution of 1:50 (under 10x lens)
-
Background
F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins, and they are a family of eukaryotic proteins characterized by an approximately 40 amino acid motif. SCF complex, a class of ubiquitin ligases, consists of invariable components, Skp1 and Cullin, and variable components of F-box proteins, which have a primary role in determining substrate specificity. The F-box proteins are divided into 3 classes: FBWs containing WD-40 domains, FBLs containing leucine-rich repeats, and FBXs containing either different protein-protein interaction modules or no recognizable motifs. FBOX9 (or FBX9) belongs to the FBXs class, and 3 isoforms produced by alternative splicing has been described.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"