FANCD2-phospho(S330) antibody

FANCD2-phospho(S330) antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

FANCD2-phospho(S330) Rabbit Polyclonal antibody. Positive WB detected in HL-60 cells. Positive IHC detected in human testis tissue. Observed molecular weight by Western-blot: 150-155kd

ELISA, WB, IHC

Human; other species not tested.

DKFZp762A223 antibody; FA D2 antibody; FA4 antibody; FACD antibody; FAD antibody; FAD2 antibody; FANCD antibody; FANCD2 antibody; FLJ23826 antibody; Protein FACD2 antibody

Rabbit IgG

This antibody was obtained by immunization of Peptide (Accession Number: NM_033084). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

FANCD2, also named as FACD and FACD2, is required for maintenance of chromosomal stability. FANCD2 promotes accurate and efficient pairing of homologs during meiosis. FANCD2 is involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. It may participate in S phase and G2 phase checkpoint activation upon DNA damage. It promotes BRCA2/FANCD1 loading onto damaged chromatin. FANCD2 may also be involved in B-cell immunoglobulin isotype switching. Defects in FANCD2 are a cause of Fanconi anemia (FA) which is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. The antibody is to phospho-Ser(330) of FANCD2.