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Product Name
FAM120A Monoclonal Antibody
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Description
Monoclonal antibody to FAM120A
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Tested applications
WB, IHC, IF
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Species reactivity
Human
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Alternative names
FAM120A antibody; C9orf10 antibody; HBVPTPAP antibody; OSSA antibody; DNAPTP1 antibody; DNAPTP5 antibody; family with sequence similarity 120A antibody
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Isotype
Mouse IgG
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Preparation
Antigen: A synthetic peptide of human FAM120A
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
IHC 1:20 - 1:50
IF 1:20 - 1:50 -
Validations
Western blot - FAM120A Monoclonal Antibody
Western blot analysis of extracts of various cell lines, using FAM120A antibody .Secondary antibody: HRP Goat Anti-Mouse IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"