Fallaxidin 4.1 peptide

Fallaxidin 4.1 peptide

• Handling and Storage of Synthetic Peptides
• Material Safety Data Sheets (MSDS)

Batch to batch variation of the purity

GLLSFLPKVIGVIGHLIHPPS

Gly-Leu-Leu-Ser-Phe-Leu-Pro-Lys-Val-Ile-Gly-Val-Ile-Gly-His-Leu-Ile-His-Pro-Pro-Ser

21

98.1%

Synthetic

Powder

Moderately active (MIC 12-100 uM) against Leuconostoc lactis and streptococcus uberis. Interestingly, C-terminal amidation increased antibacterial activity by ~4-fold, indicating the important role of positive charge (Sherman PJ et al., 2009 Biochemistry 48: 11892-901. DOI: 10.1021). The amidated peptide adopts a distorted helical structure in DPC micelles. Solid-state NMR analysis reveals the perturbation of membrane order and induces lipid domain formation in the presence of both PG and PC lipids. Updated 12/02/09. Fallaxidin 4.1 has Antibacterial activity. Fallaxidin 4.1 was found in the Eastern dwarf tree frog Litoria fallax, Australia.

Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.