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FADS1 antibody

Cat.#: 110449

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Product Information

  • Product Name
    FADS1 antibody
  • Documents
  • Description
    FADS1 Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue. Positive WB detected in mouse brain tissue. Observed molecular weight by Western-blot: 52 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    D5D antibody; Delta(5) desaturase antibody; Delta(5) fatty acid desaturase antibody; FADS1 antibody; FADS6 antibody; FADSD5 antibody; fatty acid desaturase 1 antibody; FLJ38956 antibody; FLJ90273 antibody; LLCDL1 antibody; TU12 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of FADS1 recombinant protein (Accession Number: BC007846). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IHC: 1:20-1:200

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110449(FADS1 antibody) at dilution of 1:1000

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110449(FADS1 antibody) at dilution of 1:1000

    Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using Catalog No:110449(FADS1 Antibody) at dilution of 1:200 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using Catalog No:110449(FADS1 Antibody) at dilution of 1:200 (under 10x lens)

    Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using Catalog No:110449(FADS1 Antibody) at dilution of 1:200 (under 40x lens)

    Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using Catalog No:110449(FADS1 Antibody) at dilution of 1:200 (under 40x lens)

  • Background
    FADS1, also known as Delta-5 desaturase or D5D, is a 444 amino acid protein that belongs to the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS1 is a key enzyme in polyunsaturated fatty acid (PUFA) metabolism that catalyze the conversion of linoleic acid (LA) into arachidonic acid (AA) and that of alpha-linolenic acid (ALA) into eicosapentaenoic acid (EPA).
  • References
    • Griffitts J, Tesiram Y, Reid GE, Saunders D, Floyd RA, Towner RA. In vivo MRS assessment of altered fatty acyl unsaturation in liver tumor formation of a TGF alpha/c-myc transgenic mouse model. Journal of lipid research. 50(4):611-22. 2009.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"