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Product Name
FABP7 antibody
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Description
FABP7 Rabbit Polyclonal antibody. Positive IHC detected in human gliomas tissue, human brain tissue, human breast cancer tissue. Positive WB detected in human brain tissue. Observed molecular weight by Western-blot: 15 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
B FABP antibody; BLBP antibody; Brain lipid binding protein antibody; DKFZp547J2313 antibody; FABP7 antibody; FABPB antibody; Fatty acid binding protein 7 antibody; MRG antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_001446). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110443(FABP7 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human gliomas using Catalog No:110443(FABP7 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human gliomas using Catalog No:110443(FABP7 antibody) at dilution of 1:50 (under 40x lens)
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Background
FABP7 (brain fatty acid-binding protein; BLBP) is a member of the FABP family of lipid chaperones involved in the uptake and intracellular trafficking of fatty acids. FABP7 is expressed in radial glial cells during brain development. FABP7 is up-regulated in brain tumor tissue; its expression has been associated with decreased survival times and tumor progression in patients with astrocytoma, melanoma, basal-type breast cancer, and renal cell carcinoma. This antibody is useful to label radial gial cells.
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References
- Edri R, Yaffe Y, Ziller MJ. Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors. Nature communications. 6:6500. 2015.
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