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Product Name
F7 antibody
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Description
F7 Rabbit Polyclonal antibody. Positive WB detected in human placenta tissue, human plasma tissue, mouse liver tissue. Observed molecular weight by Western-blot: 49-55 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
Coagulation factor VII antibody; Eptacog alfa antibody; PrOConvertin antibody; SPCA antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of F7 recombinant protein (Accession Number: NM_019616). Purification method: Antigen Affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
human placenta tissue were subjected to SDS PAGE followed by western blot with Catalog No:110431(F7 Antibody) at dilution of 1:300
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Background
F7(Coagulation factor VII) is also named as serum prothrombin conversion accelerator(SPCA). It is the key triggering enzyme of the extrinsic coagulation pathway. Hepatocytes are the predominant source of F7 production under normal physiologic conditions, although F7 is also expressed by monocytes/macrophages in inflammation and atherosclerosis(PMID:17018600). This protein has 2 isoforms produced by alternative splicing.
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