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Product Name
Exatecan Monoclonal Antibody(MM23L)
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Description
Product has been tested in direct ELISA.
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Tested applications
ELISA
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Species reactivity
Chemical
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Isotype
Mouse IgG2b, κ
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Preparation
Exatecan conjugated with OVA. Protein G affinity purified
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Clonality
Monoclonal
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Formulation
PBS(pH7.4)
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
ELISA: 1:5,000-1:20,000
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Validations
ELISA Binding Assay of Anti-Exatecan Antibody (MM23L) to different proteins.
ELISA analysis of Anti-Exatecan Monoclonal Antibody with Exatecan-OVA, Exatecan-BSA, OVA and BSA. Anti-Exatecan Monoclonal Antibody can bind to Exatecan-BSA or Exatecan-OVA but not carrier proteins.
ELISA Binding Assay of Anti-Exatecan Antibody (MM23L)
Immobilized Exatecan ADC at 2μg/mL (100μL/well) can bind anti-Exatecan mouse monoclonal antibody.
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Background
Exatecan is a potent inhibitor of topoisomerase I (TOP I ). In preclinical studies, exatecan was found active against multiple cancer cell lines and human breast, gastric, renal colon, ovarian, cervical, and lung xenografts models in mice. It has been developed as the payload component of antigen-dependent antibody–drug conjugates.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"