Exatecan Monoclonal Antibody(MM23L)

Cat.#: 176731

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Special Price 322.6 USD

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Product Information

  • Product Name
    Exatecan Monoclonal Antibody(MM23L)
  • Documents
  • Description
    Product has been tested in direct ELISA.
  • Tested applications
    ELISA
  • Species reactivity
    Chemical
  • Isotype
    Mouse IgG2b, κ
  • Preparation
    Exatecan conjugated with OVA. Protein G affinity purified
  • Clonality
    Monoclonal
  • Formulation
    PBS(pH7.4)
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    ELISA: 1:5,000-1:20,000
  • Validations

    ELISA Binding Assay of Anti-Exatecan Antibody (MM23L) to different proteins.

    ELISA Binding Assay of Anti-Exatecan Antibody (MM23L) to different proteins.

    ELISA analysis of Anti-Exatecan Monoclonal Antibody with Exatecan-OVA, Exatecan-BSA, OVA and BSA. Anti-Exatecan Monoclonal Antibody can bind to Exatecan-BSA or Exatecan-OVA but not carrier proteins.

    ELISA Binding Assay of Anti-Exatecan Antibody (MM23L)

    ELISA Binding Assay of Anti-Exatecan Antibody (MM23L)

    Immobilized Exatecan ADC at 2μg/mL (100μL/well) can bind anti-Exatecan mouse monoclonal antibody.

  • Background
    Exatecan is a potent inhibitor of topoisomerase I (TOP I ). In preclinical studies, exatecan was found active against multiple cancer cell lines and human breast, gastric, renal colon, ovarian, cervical, and lung xenografts models in mice. It has been developed as the payload component of antigen-dependent antibody–drug conjugates.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"