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Product Name
Human ECSIT (His Tag) recombinant protein
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Description
Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development (By similarity).
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Protein name
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
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Protein short names
SIGNALING INTERMEDIATE IN TOLL PATHWAY-EVOLUTIONARILY CONSERVED; ECSIT HOMOLOG (DROSOPHILA); ECSIT SIGNALLING INTEGRATOR; MITOCHONDRIAL; ECSIT HOMOLOG; LIKELY ORTHOLOG OF MOUSE SIGNALING INTERMEDIATE IN TOLL PATHWAY EVOLUTIONARILY CONSERVED; EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY; SITPEC; ECSIT
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Uniprot ID
Q9BQ95
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Gene Name
ECSIT
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human ECSIT (Q9BQ95-1)(Glu246-Ser431) was expressed with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human ECSIT consists of 201 amino acids and predicts a molecular mass of 22.9 KDa. It migrates as an approximately 25 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human ECSIT Protein (His Tag) SDS-PAGE
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