Human SULT1E1 (His Tag) recombinant protein

Cat.#: 502857

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Product Information

  • Product Name
    Human SULT1E1 (His Tag) recombinant protein
  • Documents
  • Description
    Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated.
  • Protein name
    Estrogen sulfotransferase
  • Protein short names
    EST; EST-1; SULT1E1; MGC34459; ST1E1; STE
  • Uniprot ID
    Q53X91
  • Gene Name
    SULT1E1; STE
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human SULT1E1 (NP_005411.1) (Asn 2-Ile 294) was expressed, with a polyhistidine tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human SULT1E1 comprises 300 amino acids and has a predicted molecular mass of 36 kDa. It migrates as an approximately 33 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 92 % as determined by SDS-PAGE
  • Validations

    Human SULT1E1 / ST1E1 Protein (His Tag) SDS-PAGE

    Human SULT1E1 / ST1E1 Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"