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Product Name
Mouse EGFL7/VE-statin (His Tag) recombinant protein
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Description
Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.
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Protein name
Epidermal growth factor-like protein 7
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Protein short names
RP11-251M1.2; ZNEU1; NEU1; RP23-70A22.2; UNQ187/PRO1449; MGC111117; EGFL7; VE-STATIN
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Uniprot ID
Q9QXT5
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Gene Name
Egfl7; Megf7
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse EGFL7 isoform 1 (Q9QXT5-1) (Glu 22-Leu 275) was fused with a polyhistidine tag at the N-terminus.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse EGFL7 consists of 273 amino acids and has a calculated molecular mass of 29.8 kDa. It migrates as an approximately 34 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Activity
Measured by the ability of the immobilized protein to support the adhesion of the HUVEC human umbilical vein endothelial cell line. When 4 x 10E4 cells/well are added to mouse EGFL7 coated plates (0.8 μg/ml, 100 μl/well), approximately >40% will adhere after one hour at 37 ℃.
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Validations
Mouse EGFL7 / VE-statin Protein (His Tag) SDS-PAGE
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