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Product Name
Mouse EphB6/Eph Receptor B6 (His Tag) recombinant protein
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Description
Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity).
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Protein name
Ephrin type-B receptor 6
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Protein short names
CEKL; EPHB6; MGC129910; MGC129911; HEP; MEP
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Uniprot ID
O08644
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Gene Name
Ephb6; Cekl
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse EPHB6 (O08644-1) (Met1-Ser587) was expressed with a C-terminal polyhistidine tag.
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Protein Species
Mouse
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Molecular weight
The recombinant mouse EPHB6 comprises 566 amino acids and has a predicted molecular mass of 61.1 kDa. The apparent molecular mass of the protein is approximately 91 and 65 kDa in SDS-PAGE under reducing conditions.
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Purity
(16.4+73.1) % as determined by SDS-PAGE
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Activity
1. Immobilized mouse EPHB6-His at 10 μg/ml (100 μl/well) can bind mouse EFNB1-Fc (Cat:503291), The EC50 of mouse EFNB1-Fc (Cat:503291) is 0.12-0.28 μg/ml.
2. Immobilized mouse EPHB6-His at 10 μg/ml (100 μl/well) can bind mouse EFNB2-Fc (Cat:504064), The EC50 of mouse EFNB2-Fc (Cat:504064) is 0.04-0.08 μg/ml. -
Validations
Mouse EphB6 Protein (His Tag) SDS-PAGE
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