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Product Name
ELK4 antibody
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Description
ELK4 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, Jurkat cells, MCF7 cells, mouse liver tissue. Observed molecular weight by Western-blot: 47kd
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Tested applications
ELISA, WB
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
ELK4 antibody; SRF accessory protein 1 antibody; SAP 1 antibody; SAP1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of ELK4 recombinant protein (Accession Number: NM_021795). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:110279(ELK4 antibody) at dilution of 1:800
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Background
ELK4, also named as SAP1, SAP-1 and SAP1, belongs to the ETS family. It forms a ternary complex with the serum response factor (SRF). ELK4 requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously. It is androgen regulated, involved in promoting cell growth, and highly expressed in a subset of prostate cancer. (PMID:19293179 )
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"