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Product Name
Human NTPDase 2 / ENTPD2 (aa 29-460, His Tag) recombinant protein
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Description
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP.
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Protein name
Ectonucleoside triphosphate diphosphohydrolase 2
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Protein short names
RP11-229P13.11-001; CD39L1; NTPDASE 2; NTPDASE2; RP23-47P18.5; NTPDASE-2; CD39 ANTIGEN-LIKE 1; ECTO-ATPASE 2; ECTO-ATPDASE 2; ECTO-ATP DIPHOSPHOHYDROLASE 2
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Uniprot ID
Q9Y5L3
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Gene Name
ENTPD2; CD39L1
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human ENTPD2 (Q9Y5L3) (Thr29-Asp460) was expressed, with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human human ENTPD2 consists of 448 amino acids and predicts a molecular mass of 49.3 KDa. It migrates as an approximately 59 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Activity
Measured by its ability to hydrolyze the 5’phosphategroups from the substrate adenosine 5’triphosphate(ATP).
The specific activity is > 5,000 pmoles/min/μg. -
Validations
Human NTPDase 2 / ENTPD2 Protein (aa 29-460, His Tag) SDS-PAGE
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