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Product Name
Human ART3 (His Tag) recombinant protein
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Description
ART3 is an arginine-specific ADP-ribosyltransferase which belongs to the Arg-specific ADP-ribosyltransferase family. ART3 catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. It is expressed specifically in testis. ART3 pseudogene is located on chromosome 11. ART3 was identified as a susceptibility gene for non-obstructive azoospermia (NOA). It is a novel therapeutic target in the treatment of NOA.
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Protein name
Ecto-ADP-ribosyltransferase 3
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Protein short names
MONO(ADP-RIBOSYL)TRANSFERASE 3; ADP-RIBOSYLTRANSFERASE 3; NAD(P)(+)--ARGININE ADP-RIBOSYLTRANSFERASE 3; ARTC3; ART3 MONO(ADP-RIBOSYL)TRANSFERASE; MONO-ADP-RIBOSYLTRANSFERASE; ECTO-ADP-RIBOSYLTRANSFERASE 3; 4930569O04RIK; ART3; ADP-RIBOSYLTRANSFERASE C2 AND C3 TOXIN-LIKE 3; MONO-ADP-RIBOSYLTRANSFERASE 3
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Uniprot ID
Q13508
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Gene Name
ART3; TMART
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ART3(AAH08397.1) (Met1-Ser362) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human ART3 consists of 347 amino acids and predicts a molecular mass of 39.6 KDa. It migrates as an approximately 49 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human ART3 Protein (His Tag) SDS-PAGE
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