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Product Name
EAAT4 antibody
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Description
EAAT4 Rabbit Polyclonal antibody. Positive WB detected in A375 cells. Observed molecular weight by Western-blot: 60-70 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
EAAT4 antibody; SLC1A6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of EAAT4 recombinant protein (Accession Number: NM_001384670). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
A375 cells were subjected to SDS PAGE followed by western blot with Catalog No:110160(SLC1A6 antibody) at dilution of 1:300
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Background
Excitatory amino acid transporter 4 (EAAT4) is a neuronal glutamate transporter responsible for the reuptake of synaptically released glutamate. The EAAT4 protein is highly enriched in Purkinje cells of the cerebellum, although it is not restricted to these cells (18770868). While the predicted molecular weight of EAAT4 is 62 kDa, considerable heterogeneity in transporter size has been reported in the brain with molecular weights ranging from 50 to 120 kDa as a result of differential glycosylation and/or phosphorylation (24056007). This antibody recognizes 60-70 kDa of EAAT4 in mouse brain and several other lysate.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"