DYRK1B antibody

DYRK1B antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

DYRK1B Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, HeLa cells, human colon tissue, human heart tissue, mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 57 kDa

ELISA, WB

Human,Mouse,Rat; other species not tested.

DYRK1B antibody; Minibrain related kinase antibody; MIRK antibody; Mirk protein kinase antibody

Rabbit IgG

This antibody was obtained by immunization of DYRK1B recombinant protein (Accession Number: XM_005259398). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

DYRK1B(dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B) is also named as MIRK. It is a member of the dyrk/minibrain family of serine/threonine kinases that mediate the transition from growth to differentiation in lower eukaryotes and mammals(PMID:15546868). DYRK1B functions as a transcriptional coactivator that is activated by co-expressed MKK3, a MAP kinase that also can activate p38 MAP kinase(PMID:14500717). The DYRK1B splice variants found in each muscle tissue exhibit approximate molecular weights of 70 and 75 kDa(PMID:12902328). It has 3 isoforms produced by alternative splicing of the molecular weight of 65-69 kDa.

• Zeng Y, Wang Y, Wu Z. miR-9 enhances the transactivation of nuclear factor of activated T cells by targeting KPNB1 and DYRK1B. American journal of physiology. Cell physiology. 308(9):C720-8. 2015.