DXd Monoclonal Antibody

Cat.#: 176730

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Special Price 322.6 USD

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Product Information

  • Product Name
    DXd Monoclonal Antibody
  • Documents
  • Description
    Product has been tested in direct ELISA.
  • Tested applications
    ELISA
  • Species reactivity
    Chemical
  • Isotype
    Mouse IgG1, κ
  • Preparation
    DXd conjugated with BSA. Protein G affinity purified
  • Clonality
    Monoclonal
  • Formulation
    PBS(pH7.4)
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    ELISA: 1:5,000-1:20,000
  • Validations

    ELISA Binding Assay of Anti-Dxd Antibody (MM438I) to different proteins.

    ELISA Binding Assay of Anti-Dxd Antibody (MM438I) to different proteins.

    ELISA analysis of Anti-Dxd Monoclonal Antibody with Dxd-BSA, BSA and Dxd ADC. Anti-Dxd Monoclonal Antibody can bind to Dxd-BSA or Dxd ADC but not carrier protein.

    ELISA Binding Assay of Anti-Dxd Antibody (MM438I)

    ELISA Binding Assay of Anti-Dxd Antibody (MM438I)

    Immobilized Dxd ADC at 2μg/mL (100μL/well) can bind anti-Dxd mouse monoclonal antibody.

  • Background
    Dxd (Deruxtecan) is a potent DNA topoisomerase I inhibitor, of 10-fold potency compared to the active metabolite of irinotecan (SN-38) in vitro. Dxd has been used as the conjugated payload of the HER2-targeting ADC (DS-8201a) and some other ADCs.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"