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Product Name
DUSP22 antibody
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Description
DUSP22 Rabbit Polyclonal antibody. Positive WB detected in Transfected HEK-293 cells, mouse kidney tissue. Positive IHC detected in human lung cancer tissue. Observed molecular weight by Western-blot: 21 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
DUSP22 antibody; FLJ35864 antibody; JKAP antibody; JNK stimulatory phosphatase 1 antibody; JSP 1 antibody; JSP1 antibody; LMW DSP2 antibody; LMWDSP2 antibody; MAP kinase phosphatase x antibody; MKP x antibody; MKPX antibody; VHX antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of DUSP22 recombinant protein (Accession Number: NM_020185). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:110119(DUSP22 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:110119(DUSP22 antibody) at dilution of 1:50 (under 40x lens)
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:110119(DUSP22 Antibody) at dilution of 1:1000
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Background
DUSP22(Dual specificity protein phosphatase 22) is also named as JSP1, LMWDSP2, MKPX. It has been demonstrated to belong to a new subgroup of small DSPs anchored at the membranes by an N-terminal myristic acid moiety and DUSP22 play a regulatory role in the JNK or p38 MAPK pathways(PMID:17384676). It has 2 isoforms produced by alternative splicing with the molecular weight of 21 kDa and 23 kDa.
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