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DSS1 antibody

Cat.#: 110030

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Special Price 239.0 USD

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Product Information

  • Product Name
    DSS1 antibody
  • Documents
  • Description
    DSS1 Rabbit Polyclonal antibody. Positive IF detected in Hela cells. Positive WB detected in HeLa cells. Observed molecular weight by Western-blot: 8-10 kDa
  • Tested applications
    ELISA, WB, IF
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    DSS1 antibody; ECD antibody; SEM1 antibody; SHFD1 antibody; Shfdg1 antibody; SHFM1 antibody; SHSF1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of DSS1 recombinant protein (Accession Number: NM_006304). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IF: 1:10-1:100

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:110030(SHFM1 antibody) at dilution of 1:300

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:110030(SHFM1 antibody) at dilution of 1:300

    Immunofluorescent analysis of Hela cells, using SHFM1 antibody Catalog No:110030 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

    Immunofluorescent analysis of Hela cells, using SHFM1 antibody Catalog No:110030 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

  • Background
    SHFM1 represents split hand/foot malformation (ectrodactyly) type 1
  • References
    • Bhatia V, Barroso SI, García-Rubio ML, Tumini E, Herrera-Moyano E, Aguilera A. BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2. Nature. 511(7509):362-5. 2014.
    • Rezano A, Kuwahara K, Yamamoto-Ibusuki M. Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival. BMC cancer. 13:562. 2013.
    • Butler LR, Densham RM, Jia J. The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response. The EMBO journal. 31(19):3918-34. 2012.
    • Rattanasopha S, Tongkobpetch S, Srichomthong C, Kitidumrongsook P, Suphapeetiporn K, Shotelersuk V. Absent expression of the osteoblast-specific maternally imprinted genes, DLX5 and DLX6, causes split hand/split foot malformation type I. Journal of medical genetics. 51(12):817-23. 2014.
    • Zhang Y, Chang FM, Huang J. DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells. Protein & cell. 5(2):124-40. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"