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DRP1 antibody

Cat.#: 110024

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Product Information

  • Product Name
    DRP1 antibody
  • Documents
  • Description
    DRP1 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, NIH/3T3 cells, Transfected HEK-293 cells. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 75-80 kDa
  • Tested applications
    ELISA, WB, IP
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    DLP1 antibody; DNM1L antibody; DRP1 antibody; DYMPLE antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of DRP1 recombinant protein (Accession Number: NM_012063). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

    IP: 1:200-1:2000

  • Validations

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110024(DNM1L,DLP1 Antibody) at dilution of 1:600

    mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:110024(DNM1L,DLP1 Antibody) at dilution of 1:600

    IP Result of anti-DNM1L,DLP1 (IP:Catalog No:110024, 4ug; Detection:Catalog No:110024 1:500) with mouse brain tissue lysate 3600ug.

    IP Result of anti-DNM1L,DLP1 (IP:Catalog No:110024, 4ug; Detection:Catalog No:110024 1:500) with mouse brain tissue lysate 3600ug.

  • Background
    DNM1L(Dynamin-1-like protein) , also known as dynamin-related protein 1 (DRP1), belongs to the dynamin family of large GTPases that mediate membrane remodeling during a variety of cellular processes. DNM1L has an important role in the division of growing mitochondria and peroxisomes and also mediates outer mitochondrial membrane fission in mammalian cells. DNM1L is ubiquitously expressed with abundant expression in skeletal muscle, heart, kidney and brain.Variable isoforms of DNM1L have been reported in a tissue-specific manner due to the alternative splicing.
  • References
    • Wang Y, Pan Y, Price A, Martin LJ. Generation and characterization of transgenic mice expressing mitochondrial targeted red fluorescent protein selectively in neurons: modeling mitochondriopathy in excitotoxicity and amyotrophic lateral sclerosis. Molecular neurodegeneration. 6:75. 2011.
    • He H, Teng H, Zhou T. Unravelling the proteome of adult rhesus monkey ovaries. Molecular bioSystems. 10(3):653-62. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"