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Product Name
DR3 antibody
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Description
DR3 Rabbit Polyclonal antibody. Positive WB detected in PC-3 cells, mouse spleen tissue, mouse thymus tissue. Observed molecular weight by Western-blot: 17-20 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
APO 3 antibody; APO3 antibody; DDR3 antibody; Death receptor 3 antibody; DR3 antibody; LARD antibody; Protein WSL antibody; Protein WSL 1 antibody; TNFRSF12 antibody; TNFRSF25 antibody; TR3 antibody; TRAMP antibody; WSL antibody; WSL 1 antibody; WSL LR antibody; WSL1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_003790). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:110011(TNFRSF25 antibody) at dilution of 1:600
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Background
TNFRSF25, also named as APO3, DDR3, DR3, TNFRSF12, WSL, WSL1, LARD, TRAMP and AIR, is a receptor for TNFSF12/APO3L/TWEAK. TNFRSF25 interacts directly with the adapter TRADD. It mediates activation of NF-kappa-B and induces apoptosis. TNFRSF25 may play a role in regulating lymphocyte homeostasis. It is constitutively and highly expressed by CD4(+)FoxP3(+) Tregs. This antibody can recognize all the isoform of TNFRSF25.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"