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Product Name
DOK7 Polyclonal Antibody
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Description
Polyclonal antibody to DOK7
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Tested applications
WB
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Species reactivity
Human, Mouse
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Alternative names
DOK7 antibody; C4orf25 antibody; CMS10 antibody; CMS1B antibody; protein Dok-7 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human DOK7
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
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Validations
Western blot - DOK7 Polyclonal Antibody
Western blot analysis of extracts of Jurkat cells, using DOK7 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"