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  • DNTTIP1 Polyclonal Antibody

DNTTIP1 Polyclonal Antibody

Cat.#: 166600

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Product Information

  • Product Name
    DNTTIP1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to DNTTIP1
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    DNTTIP1 antibody; C20orf167 antibody; Tdif1 antibody; dJ447F3.4 antibody; deoxynucleotidyltransferase terminal-interacting protein 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-329 of human DNTTIP1 (NP_443183.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:200 - 1:2000
  • Validations

    Western blot - DNTTIP1 Polyclonal Antibody

    Western blot - DNTTIP1 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using DNTTIP1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 5S.

  • Background
    Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"