DMTF1 Polyclonal Antibody

Cat.#: 163408

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Product Information

  • Product Name
    DMTF1 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to DMTF1
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    DMTF1 antibody; DMP1 antibody; DMTF antibody; MRUL antibody; hDMP1 antibody; cyclin-D-binding Myb-like transcription factor 1 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 561-760 of human DMTF1 (NP_066968.3).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - DMTF1 Polyclonal Antibody

    Western blot - DMTF1 Polyclonal Antibody

    Western blot analysis of extracts of HT-29 cells,using DMTF1 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 30s.

  • Background
    Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest (By similarity). Binds to the consensus sequence 5'-CCCG[GT]ATGT-3' (By similarity). Isoform 1 may cooperate with MYB to activate transcription of the ANPEP gene. Isoform 2 may antagonize transcriptional activation by isoform 1.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"