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  • Diuretic hormone Dippu-DH31 peptide

Diuretic hormone Dippu-DH31 peptide

Not For Human Use, Lab Use Only.

Cat.#: 312411

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* Buy 1 get 1 free (?) What is TFA?

Special Price 392.20 USD

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Product Information

  • Product Name
    Diuretic hormone Dippu-DH31 peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    GLDLGLSRGFSGSQAAKHLMGLAAANYAGGP
  • Sequence
    H-Gly-Leu-Asp-Leu-Gly-Leu-Ser-Arg-Gly-Phe-Ser-Gly-Ser-Gln-Ala-Ala-Lys-His-Leu-Met-Gly-Leu-Ala-Ala-Ala-Asn-Tyr-Ala-Gly-Gly-Pro-NH2
  • Length (aa)
    31
  • Peptide Purity (HPLC)
    97.9%
  • Molecular Formula
    C130H208N40O39S
  • Molecular Weight
    2987.3
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Dippu-DH31 is a 31-amino acid peptide diuretic hormone isolated from the cockroach Diploptera punctata. It represents a distinct type of insect diuretic hormone, exhibiting significant sequence similarity to the vertebrate calcitonin family rather than to the corticotropin-releasing factor (CRF)-like insect diuretic hormone family. The peptide stimulates fluid secretion in Malpighian tubules and increases cAMP production in certain insect species.

    Its mechanism of action differs from that of CRF-like diuretic hormones. Physiological studies indicate Dippu-DH31 likely acts via a calcium-dependent signaling pathway to influence ion transport, contrasting with the primarily cAMP-mediated action of peptides like Dippu-DH46. This is supported by its synergistic interactions with other peptides and its non-selective effect on monovalent cation transport, which leaves the urine potassium-to-sodium ratio unchanged.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Furuya K, Milchak RJ, Schegg KM, Zhang J, Tobe SS, Coast GM, Schooley DA. Cockroach diuretic hormones: characterization of a calcitonin-like peptide in insects. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6469-74. doi: 10.1073/pnas.97.12.6469. PMID: 10841553; PMCID: PMC18626.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"