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Human DEPE2 (Fc Tag) recombinant protein

Cat.#: 502841

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Product Information

  • Product Name
    Human DEPE2 (Fc Tag) recombinant protein
  • Documents
  • Description
    DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1),membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.
  • Protein name
    Dipeptidase 2
  • Protein short names
    MEMBRANE-BOUND DIPEPTIDASE 2; UNQ284/PRO323; DPEP2; F630103D06RIK; DIPEPTIDASE 2; MBD2; MBD-2; PUTATIVE MEMBRANE-BOUND DIPEPTIDASE 2
  • Uniprot ID
    Q9H4A9
  • Gene Name
    DPEP2; UNQ284/PRO323
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human DPEP2 (AAH24021.1) (Met1-Ser376) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human DPEP2/Fc is a disulfide-linked homodimer. The reduced monomer comprises 585 amino acids and has a predicted molecular mass of 65 kDa. The apparent molecular mass of the protein is approximately 43-49 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Validations

    Human MBD2 / DPEP2 Protein (Fc Tag) SDS-PAGE

    Human MBD2 / DPEP2 Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"