DIO1 Polyclonal Antibody
Polyclonal antibody to DIO1
DIO1 antibody; 5DI antibody; TXDI1 antibody; iodothyronine deiodinase 1 antibody
Antigen: A synthetic peptide of human DIO1
PBS with 0.02% sodium azide, pH7.3.
Store at 4℃. Avoid freeze / thaw cycles.
WB 1:500 - 1:2000
Western blot - DIO1 Polyclonal Antibody
Western blot analysis of extracts of HepG2 cells, using DIO1 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.
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