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  • DGKZ Polyclonal Antibody

DGKZ Polyclonal Antibody

Cat.#: 166608

Special Price 174.2 USD

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Product Information

  • Product Name
    DGKZ Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to DGKZ
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse
  • Alternative names
    DGKZ antibody; DAGK5 antibody; DAGK6 antibody; DGK-ZETA antibody; hDGKzeta antibody; diacylglycerol kinase zeta antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 808-1117 of human DGKZ (NP_001099010.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - DGKZ Polyclonal Antibody

    Western blot - DGKZ Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using DGKZ antibody at 1:300 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 1s.

  • Background
    Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity. Positively regulates insulin-induced translocation of SLC2A4 to the cell membrane in adipocytes (By similarity). Activates PIP5K1A activity via generation of phosphatidic acid.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"