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Product Name
Desmocollin 2 antibody
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Description
Desmocollin 2 Rabbit Polyclonal antibody. Positive IHC detected in human oesophagus tissue.
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Tested applications
ELISA, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
ARVD11 antibody; Cadherin family member 2 antibody; CDHF2 antibody; desmOCollin 2 antibody; DesmOCollin 3 antibody; Desmosomal glycoprotein II antibody; Desmosomal glycoprotein III antibody; DG2 antibody; DGII/III antibody; DKFZp686I11137 antibody; DSC2 antibody; DSC3 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Desm℃ollin 2 recombinant protein (Accession Number: NM_024422). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemistry of paraffin-embedded human oesophagus tissue slide using Catalog No:109898(DSC2 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human oesophagus tissue slide using Catalog No:109898(DSC2 Antibody) at dilution of 1:50 (under 40x lens)
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Background
Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelia and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.
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