-
Product Name
Mouse DLL1 / Delta-like 1 (His Tag) recombinant protein
- Documents
-
Description
May be involved in cell-to-cell communication in mammalian embryos. May have a role in cellular interactions underlying somitogenesis and development of the nervous system.
-
Protein name
Delta-like protein 1
-
Protein short names
DELTA1; DLL1; DL1; DELTA; H-DELTA-1
-
Uniprot ID
Q61483
-
Gene Name
Dll1
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the extracellular domain of mouse DLL1 (NP_031891.2) (Met 1-Gln 516) was expressed, with a polyhistidine tag at the C-terminus.
-
Protein Species
Mouse
-
Molecular weight
The recombinant mouse DLL1 consists of 506 amino acids and has a predicted molecular mass of 55 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm DLL1 is approximately 65 kDa due to glycosylation.
-
Purity
> 95 % as determined by SDS-PAGE
-
Activity
1. Measured by its ability to bind human NOTCH1 in a functional ELISA.
2. Measured by the ability of the immobilized protein to enhance BMP2 induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-20 μg/mL. -
Validations
Mouse DLL1 / Delta-1 Protein (His Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"